Using Ensemble Models in the Histological Examination of Tissue Abnormalities

Classification models for the automatic detection of abnormalities on histological samples do exists, with an active debate on the cost associated with false negative diagnosis (underdiagnosis) and false positive diagnosis (overdiagnosis). Current models tend to underdiagnose, failing to recognize a potentially fatal disease. The objective of this study is to investigate the possibility of automatically identifying abnormalities in tissue samples through the use of an ensemble model on data generated by histological examination and to minimize the number of false negative cases. Keywords—Histology, data mining, CART, logistic regression, ensemble model, classification, breast cancer